Risk Factors and Prevalence of Tuberculosis in Urban Slum Populations of Kishorgonj, Bangladesh
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Abstract
Background: Tuberculosis (TB) is the major cause of mortality and morbidity among infectious diseases. Globally, an estimated 10 million people develop TB and over a million deaths occur annually. It remains a significant public health concern, particularly in developing countries with suboptimal sanitation and healthcare infrastructure. Objective: This study aims to identify risk factors and determine the prevalence of tuberculosis (TB) among urban slum populations in Kishorgonj, Bangladesh. Methods: A cross-sectional study was conducted from January to June 2024, involving several slum areas in Kishorgonj. A total of 43 confirmed TB cases were included. Data were collected using structured questionnaires and clinical examinations. Risk factors analyzed included demographic details, socioeconomic status, living conditions, and history of TB contact. Statistical analyses included descriptive statistics, prevalence calculation, odds ratios (OR) with 95% confidence intervals (CI), chi-square tests, and logistic regression. Results: The study found the prevalence of TB ranging from 4.0% to 10.0% across different slum areas. Significant risk factors included a history of TB contact (OR: 3.2, 95% CI: 1.5-6.7), poor living conditions (OR: 4.1, 95% CI: 2.0-8.4), and malnutrition (OR: 2.5, 95% CI: 1.2-5.2). Smoking, lack of formal education, unemployment, and temporary housing were also associated with increased TB risk but to a lesser extent. Conclusion: The study highlights the high prevalence of TB in urban slum populations and identifies key risk factors. Addressing poor living conditions, malnutrition, and inadequate housing could significantly reduce TB incidence in these communities. Targeted public health interventions are needed to improve living standards and prevent TB spread.
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References
1. World Health Organization. Global tuberculosis control 2011: WHO report 2011. Geneva: World Health Organization. 2011.
2. Hayward AC, Darton T, Van-Tam JN, Watson JM, Coker R, Schwoebel V. Epidemiology and control of tuberculosis in Western European cities. The international journal of tuberculosis and lung disease. 2003 Aug 1;7(8):751-7.
3. Braden CR, Templeton GL, Cave MD, Valway S, Onorato IM, Castro KG, Moers D, Yang Z, Stead WW, Bates JH. Interpretation of restriction fragment length polymorphism analysis of Mycobacterium tuberculosis isolates from a state with a large rural population. The Journal of infectious diseases. 1997 Jun 1;175(6):1446-52.
4. Hossain S, Quaiyum MA, Zaman K, Banu S, Husain MA, Islam MA, Cooreman E, Borgdorff M, Lönnroth K, Salim AH, van Leth F. Socio economic position in TB prevalence and access to services: results from a population prevalence survey and a facility-based survey in Bangladesh.
5. Islam MS, Sultana R, Hasan MA, Horaira MA, Islam MA. Prevalence of Tuberculosis: Present Status and Overview of Its Control System in Bangladesh. Int. J. Life. Sci. Scienti. Res. 2017 Nov;3(6):1471-5.
6. Ford CM, Bayer AM, Gilman RH, Onifade D, Acosta C, Cabrera L, Vidal C, Evans CA. Factors associated with delayed tuberculosis test-seeking behavior in the Peruvian Amazon. The American journal of tropical medicine and hygiene. 2009 Dec;81(6):1097.
7. Asch S, Leake B, Anderson R, Gelberg L. Why do symptomatic patients delay obtaining care for tuberculosis?. American journal of respiratory and critical care medicine. 1998 Apr 1;157(4):1244-8.
8. Zaman K, Hossain S, Banu S, Quaiyum MA, Barua PC, Salim MH, Begum V, Islam MA, Ahmed J, Rifat M, Cooreman E. Prevalence of smear-positive tuberculosis in persons aged⩾ 15 years in Bangladesh: results from a national survey, 2007–2009. Epidemiology & Infection. 2012 Jun;140(6):1018-27.
9. Banu S, Rahman MT, Uddin MK, Khatun R, Ahmed T, Rahman MM, Husain MA, van Leth F. Epidemiology of tuberculosis in an urban slum of Dhaka City, Bangladesh. PloS one. 2013 Oct 21;8(10):e77721.
10. Banu S, Uddin MK, Islam MR, Zaman K, Ahmed T, Talukder AH, Rahman MT, Rahim Z, Akter N, Khatun R, Brosch R. Molecular epidemiology of tuberculosis in rural Matlab, Bangladesh. The International Journal of Tuberculosis and Lung Disease. 2012 Mar 1;16(3):319-26.
11. Van Embden JD, Cave MD, Crawford JT, Dale JW, Eisenach KD, Gicquel B, Hermans P, Martin C, McAdam R, Shinnick TM. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. Journal of clinical microbiology. 1993 Feb;31(2):406-9.
12. Supply P, Magdalena J, Himpens S, Locht C. Identification of novel intergenic repetitive units in a mycobacterial two‐component system operon. Molecular microbiology. 1997 Dec;26(5):991-1003.
13. Supply P, Mazars E, Lesjean S, Vincent V, Gicquel B, Locht C. Variable human minisatellite‐like regions in the Mycobacterium tuberculosis genome. Molecular microbiology. 2000 May;36(3):762-71.
14. Hawkey PM, Smith EG, Evans JT, Monk P, Bryan G, Mohamed HH, Bardhan M, Pugh RN. Mycobacterial interspersed repetitive unit typing of Mycobacterium tuberculosis compared to IS 6110-based restriction fragment length polymorphism analysis for investigation of apparently clustered cases of tuberculosis. Journal of Clinical Microbiology. 2003 Aug;41(8):3514-20.
15. Mazars E, Lesjean S, Banuls AL, Gilbert M, Vincent V, Gicquel B, Tibayrenc M, Locht C, Supply P. High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology. Proceedings of the national academy of Sciences. 2001 Feb 13;98(4):1901-6.
16. Noykhovich E, Mookherji S, Roess A. The risk of tuberculosis among populations living in slum settings: a systematic review and meta-analysis. Journal of Urban Health. 2019 Apr 15;96:262-75.
17. Lee JY, Kwon N, Goo GY, Cho SI. Inadequate housing and pulmonary tuberculosis: a systematic review. BMC Public Health. 2022 Mar 30;22(1):622.
18. Reichler MR, Khan A, Yuan Y, Chen B, McAuley J, Mangura B, Sterling TR. Duration of exposure among close contacts of patients with infectious tuberculosis and risk of latent tuberculosis infection. Clinical Infectious Diseases. 2020 Oct 1;71(7):1627-34.
19. World Health Organization. Health in development. 1996.
20. Hasan H, Rahman MH, Haque MA, Rahman MS, Ali MS, Sultana S. Nutritional management in patients with chronic kidney disease: A focus on renal diet. Asia Pacific Journal of Medical Innovations. 2024 ;1(1):34-40.
21. Patwari SQ. Public Health during the Global Pandemic Covid-19: Intervening, Perceiving and Incorporating.
22. Ahasan MM, Patwari MS, Yamaguchi M. Risk of eating disorders and the relationship with interest in modern culture among young female students in a university in Bangladesh: a cross-sectional study. BMC Women's Health. 2023;23(1):35.
23. Patwari SQ. Transforming Rural Health: The Impact of Telehealth on Access and Care. TAJ. 2021;34(2):51-56. doi:10.3329/taj.v34i2.0255
24. Mashiusjaman M, Patwari SQ, Siddique MA, Haider SM. Infant feeding pattern of employed mothers in Dhaka city of Bangladesh.
25. Patwari SQ. Rise of E-Cigarettes: Implications for Public Health and Policy. TAJ. 2017;30(2):43-51. doi:10.3329/taj.v30i2.0254
26. Islam T, Chakma S, Bhuiyan MA, Rahman MN. Assessment of Bangladeshi mothers’ knowledge and awareness on childhood tuberculosis: A cross sectional study. Science. 2014;2(4):309-15.